ncRNA name | IMPDH1 shRNA |
ncRNA Category | shRNA |
Disease name | retinitis pigmentosa (RP) |
Species | Mus musculus |
Tissues/Cell_line | retinas |
Methods | shRNA knockdown, qRT-PCR, Western blot, immunostaining |
Expression pattern | associated |
Functional description | The use of rAAV2/5 vectors expressing shRNA targeting mutant IMPDH1 prevents photoreceptor degeneration, and preserves synaptic connectivity in a mouse model of RP10. |
PubMed ID | 20238059 |
Year | 2010 |
Title | Protection of photoreceptors in a mouse model of RP10. |
Drug-related ncRNA | NA |
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